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S Mongiorgi Selected Research

perifosine

6/2008The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism.

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S Mongiorgi Research Topics

Disease

3Myelodysplastic Syndromes (Myelodysplastic Syndrome)
05/2012 - 01/2008
1Anemia
12/2012
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
02/2011
1Leukemia
06/2008
1Neoplasms (Cancer)
06/2008
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
06/2008
1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
06/2008

Drug/Important Bio-Agent (IBA)

3Azacitidine (5 Azacytidine)FDA Link
05/2012 - 01/2008
2Phosphoinositide Phospholipase CIBA
05/2012 - 02/2011
1ErythropoietinFDA Link
12/2012
1Phospholipase C betaIBA
05/2012
1Proteins (Proteins, Gene)FDA Link
05/2012
1Valproic Acid (Depakote)FDA LinkGeneric
02/2011
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
06/2008
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
06/2008
1Membrane Transport Proteins (Biological Pump)IBA
06/2008
1perifosineIBA
06/2008

Therapy/Procedure

1Therapeutics
05/2012
1Drug Therapy (Chemotherapy)
06/2008